Integrin αvβ6 Promotes TGF-β1-dependent Myofibroblastic Transdifferentiation in Oral Submucous Fibrosis
Integrin αvβ6 Promotes TGF-β1-dependent Myofibroblastic Transdifferentiation in Oral Submucous Fibrosis Oral submucous fibrosis (OSF) is a chronic progressive fibrosing disorder of the oral cavity. Commonly in fibrosis, TGF-β1 promotes the transdifferentiation of fibroblasts into α-smooth muscle actin (SMA)-secreting myofibroblasts. Integrin αvβ6 is not detectable on normal oral keratinocytes but is upregulated during tissue remodelling. αvβ6 […]
CIDR – Center of Innovative Dental Research
CIDR Center of Innovative Dental Research The aim of Centre of Innovative Dental Research is to conduct qualitative and quantitative study related to dentistry. This center also conducts case based studies and clinical trials on dental biomaterials. The objective of this research group is to provide an opportunity for faculty to actively engage in research […]