Bone regeneration has gained attention for the past decades in the field of tissue engineering.  While constant research on the materials applied in this field sometimes it is necessary to evaluate the technique of fabrication and different process involved in characterization. The current day research focus upon such materials which requires less time and are more efficient and biocompatible with the human biological system. The designing of scaffold for bone repair it is a challenge to compete with the controlled porosity of the scaffold over the bone and to have maximum success in the scaffold, it must have adequate size porosity and evenly distributed pores. Current study is based on the fabrication of porous ceramic hydroxyapatite (HA) scaffold by a novel biological gas foaming technique for its fabrication. This study is based on the production of Nano sized and Micro sized porous scaffolds by using yeast cells with sugar as a new gas foaming technique, result shows a controlled porosity distribution and even sized pores which is essential for controlled cellular adhesion, extracellular matrix deposition and altogether contributes in bone formation and repair of the diseased bone or traumatized bone.

This scaffold also demonstrates better physical and chemical properties due to its chemical composition and uniformity of pores. This technique is less time consuming and more efficient for bone regeneration applications.